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SMILES: Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(C)c1

InChI Key: InChIKey=UIMDDWYVJDMJMX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 220966   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220966 (US9302996, 114 | US9302996, 81) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C21H21F3N4O3/c1-11-6-16(31-10-20(3,4)19(29)30)25-8-14(11)13-5-12(2)17(26-7-13)18-27-9-15(28-18)21(22,23)24/h5-9H,10H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM220966 (US9302996, 114 | US9302996, 81) Show SMILES Cc1cc(OCC(C)(C)C(O)=O)ncc1-c1cnc(-c2ncc([nH]2)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C21H21F3N4O3/c1-11-6-16(31-10-20(3,4)19(29)30)25-8-14(11)13-5-12(2)17(26-7-13)18-27-9-15(28-18)21(22,23)24/h5-9H,10H2,1-4H3,(H,27,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.4	30
MITSUBISHI TANABE PHARMA CORPORATION US Patent					Assay Description As a buffer to be used in the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH 7.4), 200 mM Sucrose, 20 mM MgCl2, 0.125% Bovine Serum Albumin (BSA) w...				US Patent US9302996 (2016) BindingDB Entry DOI: 10.7270/Q2TM790N
					More data for this Ligand-Target Pair