BDBM221127 US9303012, 53

SMILES: OC[C@@H]1CC(F)(F)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1

InChI Key: InChIKey=SGWOEOKFLVHZKM-LBPRGKRZSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 221127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM221127 (US9303012, 53) Show SMILES OC[C@@H]1CC(F)(F)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 |r| Show InChI InChI=1S/C18H21F4N3O3/c19-17(20)5-12(6-26)25(10-17)16(27)13-3-4-14(24-8-18(21,22)9-24)15(23-13)28-7-11-1-2-11/h3-4,11-12,26H,1-2,5-10H2/t12-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM221127 (US9303012, 53) Show SMILES OC[C@@H]1CC(F)(F)CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 |r| Show InChI InChI=1S/C18H21F4N3O3/c19-17(20)5-12(6-26)25(10-17)16(27)13-3-4-14(24-8-18(21,22)9-24)15(23-13)28-7-11-1-2-11/h3-4,11-12,26H,1-2,5-10H2/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.70	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair