BDBM221145 US9303012, 71

SMILES: FC1(F)CN(C1)c1ccc(nc1OCC1CC1)C(=O)N1CC2(C1)CS(=O)(=O)C2

InChI Key: InChIKey=WIRKLNRRFRQIMA-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 221145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM221145 (US9303012, 71) Show SMILES FC1(F)CN(C1)c1ccc(nc1OCC1CC1)C(=O)N1CC2(C1)CS(=O)(=O)C2 Show InChI InChI=1S/C18H21F2N3O4S/c19-18(20)8-22(9-18)14-4-3-13(21-15(14)27-5-12-1-2-12)16(24)23-6-17(7-23)10-28(25,26)11-17/h3-4,12H,1-2,5-11H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM221145 (US9303012, 71) Show SMILES FC1(F)CN(C1)c1ccc(nc1OCC1CC1)C(=O)N1CC2(C1)CS(=O)(=O)C2 Show InChI InChI=1S/C18H21F2N3O4S/c19-18(20)8-22(9-18)14-4-3-13(21-15(14)27-5-12-1-2-12)16(24)23-6-17(7-23)10-28(25,26)11-17/h3-4,12H,1-2,5-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	444	n/a	n/a	n/a	37
HOFFMAN-LA ROCHE INC. US Patent					Assay Description CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...				US Patent US9303012 (2016) BindingDB Entry DOI: 10.7270/Q2FF3R7H
					More data for this Ligand-Target Pair