BDBM221860 US9314468, Table 7, Compound 147
SMILES: C(CN(Cc1nccc2c3ccccc3n(CCC3CCOCC3)c12)[C@H]1CCCc2cccnc12)CN1CCNCC1
InChI Key: InChIKey=IBIHADAFGHQXNB-XIFFEERXSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 4 (CXCR4) (Homo sapiens (Human)) | BDBM221860 (US9314468, Table 7, Compound 147) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | 37 |
Altiris Therapeutics, Inc. US Patent | Assay Description Functional modulation of CXCR4 was determined by calcium mobilization assay using leukemic lymphoid CEM cells, which naturally express high levels of... | US Patent US9314468 (2016) BindingDB Entry DOI: 10.7270/Q2DF6Q2P | |||||||||||
More data for this Ligand-Target Pair |