null
SMILES: Cn1c2c3C(COC(CO)Cn3c(-c3cccc(c3)C#N)c2c(=O)n(C)c1=O)c1nc(Cl)cs1
InChI Key: InChIKey=AZHPUIDNPSAXAQ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis transmembrane conductance regulator (Cricetulus griseus (Chinese hamster)) | BDBM221996 (US9303035, 14) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.96 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh... | US Patent US9303035 (2016) BindingDB Entry DOI: 10.7270/Q2SQ8Z7R | |||||||||||
More data for this Ligand-Target Pair |