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SMILES: Cc1cccc(c1)-c1nc2cc(ccc2c(=O)o1)[N+]([O-])=O

InChI Key: InChIKey=YUVHBYMEUKMYSH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 222126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymotrypsinogen A (Bos taurus (bovine))	BDBM222126 (2-(3-Methylphenyl)-7-nitro-4H-3,1-benzoxazin-4-one...) Show SMILES Cc1cccc(c1)-c1nc2cc(ccc2c(=O)o1)[N+]([O-])=O Show InChI InChI=1S/C15H10N2O4/c1-9-3-2-4-10(7-9)14-16-13-8-11(17(19)20)5-6-12(13)15(18)21-14/h2-8H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.62E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description The change in optical density per minute (OD/min) was obtained by incorporating various concentrations of compounds over a range of substrate (SPpNA)...				Bioorg Chem 70: 210-221 (2017) Article DOI: 10.1016/j.bioorg.2017.01.001 BindingDB Entry DOI: 10.7270/Q2QR4W00
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM222126 (2-(3-Methylphenyl)-7-nitro-4H-3,1-benzoxazin-4-one...) Show SMILES Cc1cccc(c1)-c1nc2cc(ccc2c(=O)o1)[N+]([O-])=O Show InChI InChI=1S/C15H10N2O4/c1-9-3-2-4-10(7-9)14-16-13-8-11(17(19)20)5-6-12(13)15(18)21-14/h2-8H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.41E+4	n/a	n/a	n/a	n/a	7.6	n/a
University of Karachi					Assay Description The α-chymotrypsin inhibition activity was evaluated in 50 mM Tris-HCl buffer pH 7.6 with 10 mM CaCl2. α-Chymotrypsin (bovine pancreas) at ...				Bioorg Chem 70: 210-221 (2017) Article DOI: 10.1016/j.bioorg.2017.01.001 BindingDB Entry DOI: 10.7270/Q2QR4W00
					More data for this Ligand-Target Pair