BDBM222184 6-(Dimethylamino)-3-(3'-nitrophenyl)-2,3-dihydronaphtho[1,8-de][1,2]thiazine 1,1-dioxide (7f)

SMILES: CN(C)c1ccc2C(NS(=O)(=O)c3cccc1c23)c1cccc(c1)[N+]([O-])=O

InChI Key: InChIKey=DMUMVDROXAUWIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alkaline phosphatase, tissue-nonspecific isozyme (Bos taurus (Cattle))	BDBM222184 (6-(Dimethylamino)-3-(3'-nitrophenyl)-2,3-dihyd...) Show SMILES CN(C)c1ccc2C(NS(=O)(=O)c3cccc1c23)c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C19H17N3O4S/c1-21(2)16-10-9-15-18-14(16)7-4-8-17(18)27(25,26)20-19(15)12-5-3-6-13(11-12)22(23)24/h3-11,19-20H,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	9.8	37
University of Karachi					Assay Description Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...				Bioorg Chem 71: 10-18 (2017) Article DOI: 10.1016/j.bioorg.2017.01.008 BindingDB Entry DOI: 10.7270/Q26Q1W36
					More data for this Ligand-Target Pair