BDBM222217 4-(4,5-Diphenyl-1H-imidazol-2-yl)-3-(3-nitrophenyl)-1-phenyl-1H-pyrazole (2f)

SMILES: [O-][N+](=O)c1cccc(c1)-c1nn(cc1-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1)-c1ccccc1

InChI Key: InChIKey=RRQJLAVKHMFNKC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM222217 (4-(4,5-Diphenyl-1H-imidazol-2-yl)-3-(3-nitrophenyl...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1nn(cc1-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C30H21N5O2/c36-35(37)25-18-10-15-23(19-25)27-26(20-34(33-27)24-16-8-3-9-17-24)30-31-28(21-11-4-1-5-12-21)29(32-30)22-13-6-2-7-14-22/h1-20H,(H,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.28E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of the Punjab; Kinnaird College for Women					Assay Description At 37 °C, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c...				Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86
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