BDBM222889 US9315499, 1006

SMILES: Clc1ccc(CNC(=O)c2cc3cccnc3n(CC(=O)N3CC4(CC4)C3)c2=O)cc1

InChI Key: InChIKey=QXXZFXDCUHTDIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222889 (US9315499, 1006) Show SMILES Clc1ccc(CNC(=O)c2cc3cccnc3n(CC(=O)N3CC4(CC4)C3)c2=O)cc1 Show InChI InChI=1S/C23H21ClN4O3/c24-17-5-3-15(4-6-17)11-26-21(30)18-10-16-2-1-9-25-20(16)28(22(18)31)12-19(29)27-13-23(14-27)7-8-23/h1-6,9-10H,7-8,11-14H2,(H,26,30)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair