BDBM222911 US9315499, 4034

SMILES: Cn1cnc(c1)-c1cnc2n(CC(=O)N3CC(C)(F)C3)c(=O)c(cc2c1)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=KSVRMTKXQSHLJJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222911   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222911 (US9315499, 4034) Show SMILES Cn1cnc(c1)-c1cnc2n(CC(=O)N3CC(C)(F)C3)c(=O)c(cc2c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C26H24ClFN6O3/c1-26(28)13-33(14-26)22(35)12-34-23-17(7-18(10-29-23)21-11-32(2)15-31-21)8-20(25(34)37)24(36)30-9-16-3-5-19(27)6-4-16/h3-8,10-11,15H,9,12-14H2,1-2H3,(H,30,36)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair