BDBM222920 US9315499, 6001

SMILES: COc1c(cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc12)C(=O)NCc1ccc(Cl)cc1)-c1sc(C)nc1C

InChI Key: InChIKey=KUNSISDEAYOPPR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222920 (US9315499, 6001) Show SMILES COc1c(cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc12)C(=O)NCc1ccc(Cl)cc1)-c1sc(C)nc1C Show InChI InChI=1S/C29H30ClN5O4S/c1-16-25(40-17(2)33-16)22-12-31-26-20(24(22)39-5)10-21(27(37)32-11-18-6-8-19(30)9-7-18)28(38)35(26)13-23(36)34-14-29(3,4)15-34/h6-10,12H,11,13-15H2,1-5H3,(H,32,37)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
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