BDBM222921 US9315499, 6003

SMILES: COc1c(cnc2n(CC(=O)N3CCC(CO)C3)c(=O)c(cc12)C(=O)NCc1ccc(Cl)cc1)-c1cnn(C)c1

InChI Key: InChIKey=UIVCEJAUMQQCDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222921   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222921 (US9315499, 6003) Show SMILES COc1c(cnc2n(CC(=O)N3CCC(CO)C3)c(=O)c(cc12)C(=O)NCc1ccc(Cl)cc1)-c1cnn(C)c1 Show InChI InChI=1S/C28H29ClN6O5/c1-33-14-19(11-32-33)23-12-30-26-21(25(23)40-2)9-22(27(38)31-10-17-3-5-20(29)6-4-17)28(39)35(26)15-24(37)34-8-7-18(13-34)16-36/h3-6,9,11-12,14,18,36H,7-8,10,13,15-16H2,1-2H3,(H,31,38)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair