BDBM222922 US9315499, 6005

SMILES: CC1CN(C1)C(=O)Cn1c2ncc(-c3cnn(C)c3)c(-c3cnc(N)nc3)c2cc(C(=O)NCc2ccc(Cl)cc2)c1=O

InChI Key: InChIKey=WPJXQBMAKCNAKW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase (Human cytomegalovirus (HCMV strain AD169) )	BDBM222922 (US9315499, 6005) Show SMILES CC1CN(C1)C(=O)Cn1c2ncc(-c3cnn(C)c3)c(-c3cnc(N)nc3)c2cc(C(=O)NCc2ccc(Cl)cc2)c1=O Show InChI InChI=1S/C30H28ClN9O3/c1-17-13-39(14-17)25(41)16-40-27-22(7-23(29(40)43)28(42)34-8-18-3-5-21(31)6-4-18)26(19-9-35-30(32)36-10-19)24(12-33-27)20-11-37-38(2)15-20/h3-7,9-12,15,17H,8,13-14,16H2,1-2H3,(H,34,42)(H2,32,35,36)	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair