BDBM222923 US9315499, 6008

SMILES: Cn1cc(cn1)-c1cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc2c1N1CC(O)C1)C(=O)NCc1ccc(Cl)cc1

InChI Key: InChIKey=VSQCTGLXTXAVIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA polymerase catalytic subunit (Human cytomegalovirus (HCMV strain AD169) )	BDBM222923 (US9315499, 6008) Show SMILES Cn1cc(cn1)-c1cnc2n(CC(=O)N3CC(C)(C)C3)c(=O)c(cc2c1N1CC(O)C1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C30H32ClN7O4/c1-30(2)16-37(17-30)25(40)15-38-27-22(8-23(29(38)42)28(41)33-9-18-4-6-20(31)7-5-18)26(36-13-21(39)14-36)24(11-32-27)19-10-34-35(3)12-19/h4-8,10-12,21,39H,9,13-17H2,1-3H3,(H,33,41)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	180	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The assay conditions are the following: 10 mM HEPES pH 7.5, 25 mM KCl, 7.5 mM NaCl, 5 mM MgCl2, 0.2 mg BSA/mL, 1 mM TCEP, 1.5% glycerol, 5% DMSO, 235...				US Patent US9315499 (2016) BindingDB Entry DOI: 10.7270/Q2028QCZ
					More data for this Ligand-Target Pair