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SMILES: Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cc4cn[nH]c(=O)c34)cccc12

InChI Key: InChIKey=VKNUMKHLDVNTIY-DOTOQJQBSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222932   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase SYK [2-635]


(Homo sapiens (Human))		BDBM222932
PNG
(US9315500, 2.2)
Show SMILES Cn1ccc2c(Nc3nc(N[C@@H]4CCCC[C@@H]4N)cc4cn[nH]c(=O)c34)cccc12
Show InChI InChI=1S/C22H25N7O/c1-29-10-9-14-16(7-4-8-18(14)29)26-21-20-13(12-24-28-22(20)30)11-19(27-21)25-17-6-3-2-5-15(17)23/h4,7-12,15,17H,2-3,5-6,23H2,1H3,(H,28,30)(H2,25,26,27)/t15-,17+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 0.600n/an/an/an/a7.530



NOVARTIS AG

US Patent


Assay Description
All assays were performed in 384 well microtiter plates. Each assay plate contained 8-point serial dilutions for 40 test compounds, as well as four 8...

US Patent US9315500 (2016)


BindingDB Entry DOI: 10.7270/Q2V986WN
More data for this
Ligand-Target Pair