BDBM222989 US9315518, 25-5

SMILES: CN1c2nc(ccc2N(CC2CC2(F)F)S1(=O)=O)C1CCCNC1

InChI Key: InChIKey=HOHKQQOZBQXJFV-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 222989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
mGluR2 and G alpha 16 (Homo sapiens (Human))	BDBM222989 (US9315518, 25-5) Show SMILES CN1c2nc(ccc2N(CC2CC2(F)F)S1(=O)=O)C1CCCNC1 Show InChI InChI=1S/C15H20F2N4O2S/c1-20-14-13(5-4-12(19-14)10-3-2-6-18-8-10)21(24(20,22)23)9-11-7-15(11,16)17/h4-5,10-11,18H,2-3,6-9H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	359	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The compounds of the present invention may be tested in a fluorescence laser imaging plate reader (FLIPR) based assay. This assay is a common functio...				US Patent US9315518 (2016) BindingDB Entry DOI: 10.7270/Q2G44P5C
					More data for this Ligand-Target Pair