BDBM223080 (E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1yl)ethylidene)isonicotino hydrazide (3j)
SMILES: C\C(=N/NC(=O)c1ccncc1)N1N=C(CC1c1ccccc1)c1ccc(F)cc1
InChI Key: InChIKey=IBRAYHGZVRBRCQ-WGOQTCKBSA-N
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5'-nucleotidase (Homo sapiens (Human)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Intestinal alkaline phosphatase (IAP) (Bos taurus (Cattle)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.98E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tissue non-specific alkaline phosphatase (TNAP) (Bos taurus (Cattle)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.06E+3 | n/a | n/a | n/a | n/a | 9.8 | 37 |
Quaid-I-Azam University | Assay Description The assay conditions were optimized with some changes in formerly reported spectrophotometric method. The composition of assay buffer of pH 9.8 was a... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ecto-5'-nucleotidase (e5'NT) (Rattus norvegicus (Rat)) | BDBM223080 ((E)-N'-(1-(3-(4-fluorophenyl)-5-phenyl-4,5-dih...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 360 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Quaid-I-Azam University | Assay Description The enzymatic assay of both human and rat ecto-5'-nucleotidase were performed with slight modifications in the previously described method. The stock... | Chem Biol Drug Des 89: 365-370 (2017) Article DOI: 10.1111/cbdd.12861 BindingDB Entry DOI: 10.7270/Q2F47N10 | |||||||||||
More data for this Ligand-Target Pair |