null
SMILES: COc1cc(NS(=O)(=O)c2ccc(NS(=O)(=O)c3c(C)noc3C)cc2)nc(OC)n1
InChI Key: InChIKey=SSDWSTAYENJABB-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human)) | BDBM223474 (US9320734, 415) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent | Assay Description Inhibition of AKT was measured by Western blots using specific antibodies against phospho-Ser473-AKT in HT-29 lung cancer cells. Inhibition of the ph... | US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human)) | BDBM223474 (US9320734, 415) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 6.27E+3 | n/a | n/a | n/a | n/a | n/a |
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent | Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco... | US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM | |||||||||||
More data for this Ligand-Target Pair |