BDBM223575 US9321752, 16-2

SMILES: Cn1ccc2ccc(\C=C\c3cc(\C=C\c4ccc(OCc5ccccn5)cc4F)n[nH]3)cc12

InChI Key: InChIKey=FMJHRFDUJYAXSB-NSJFVGFPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM223575 (US9321752, 16-2) Show SMILES Cn1ccc2ccc(\C=C\c3cc(\C=C\c4ccc(OCc5ccccn5)cc4F)n[nH]3)cc12 Show InChI InChI=1S/C28H23FN4O/c1-33-15-13-22-7-5-20(16-28(22)33)6-10-23-17-24(32-31-23)11-8-21-9-12-26(18-27(21)29)34-19-25-4-2-3-14-30-25/h2-18H,19H2,1H3,(H,31,32)/b10-6+,11-8+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	600	n/a	n/a	n/a	n/a	7.6	n/a
GREEN TECH CO., LTD. US Patent					Assay Description Recombinant three-repeat microtubule-binding domain (3R-MBD) of tau protein was expressed in E. coli and was purified and used for the experiment. Th...				US Patent US9321752 (2016) BindingDB Entry DOI: 10.7270/Q2T72G92
					More data for this Ligand-Target Pair