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SMILES: Cn1cccc1\C=C\c1cc(\C=C\c2ccc(OCc3ccccn3)cc2)n[nH]1

InChI Key: InChIKey=DJWKUZSCACSQRQ-OFJXCKHESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223578   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Microtubule-associated protein tau


(Homo sapiens (Human))		BDBM223578
PNG
(US9321752, 20-3)
Show SMILES Cn1cccc1\C=C\c1cc(\C=C\c2ccc(OCc3ccccn3)cc2)n[nH]1
Show InChI InChI=1S/C24H22N4O/c1-28-16-4-6-23(28)12-11-21-17-20(26-27-21)10-7-19-8-13-24(14-9-19)29-18-22-5-2-3-15-25-22/h2-17H,18H2,1H3,(H,26,27)/b10-7+,12-11+
PDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/a7.6n/a



GREEN TECH CO., LTD.

US Patent


Assay Description
Recombinant three-repeat microtubule-binding domain (3R-MBD) of tau protein was expressed in E. coli and was purified and used for the experiment. Th...

US Patent US9321752 (2016)


BindingDB Entry DOI: 10.7270/Q2T72G92
More data for this
Ligand-Target Pair