BDBM223582 US9321752, 32-5

SMILES: Cc1cc(OCc2ccccn2)ccc1\C=C\c1cc(\C=C\c2cccn2C)[nH]n1

InChI Key: InChIKey=AXZRPRBDTRVVHE-REVVXPLQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 223582   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau (Homo sapiens (Human))	BDBM223582 (US9321752, 32-5) Show SMILES Cc1cc(OCc2ccccn2)ccc1\C=C\c1cc(\C=C\c2cccn2C)[nH]n1 Show InChI InChI=1S/C25H24N4O/c1-19-16-25(30-18-23-6-3-4-14-26-23)13-9-20(19)8-10-21-17-22(28-27-21)11-12-24-7-5-15-29(24)2/h3-17H,18H2,1-2H3,(H,27,28)/b10-8+,12-11+	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	640	n/a	n/a	n/a	n/a	7.6	n/a
GREEN TECH CO., LTD. US Patent					Assay Description Recombinant three-repeat microtubule-binding domain (3R-MBD) of tau protein was expressed in E. coli and was purified and used for the experiment. Th...				US Patent US9321752 (2016) BindingDB Entry DOI: 10.7270/Q2T72G92
					More data for this Ligand-Target Pair