BDBM224903 US9321756, 155

SMILES: Cc1cn(cn1)-c1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1

InChI Key: InChIKey=NOVOUDRJIQLPML-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224903   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM224903 (US9321756, 155) Show SMILES Cc1cn(cn1)-c1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C19H15N7S/c1-11-9-26(10-22-11)17-4-2-3-16(23-17)14-8-21-15-6-5-12(7-13(14)15)18-24-25-19(20)27-18/h2-10,21H,1H3,(H2,20,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.425	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM224903 (US9321756, 155) Show SMILES Cc1cn(cn1)-c1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C19H15N7S/c1-11-9-26(10-22-11)17-4-2-3-16(23-17)14-8-21-15-6-5-12(7-13(14)15)18-24-25-19(20)27-18/h2-10,21H,1H3,(H2,20,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.25	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM224903 (US9321756, 155) Show SMILES Cc1cn(cn1)-c1cccc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(N)s1 Show InChI InChI=1S/C19H15N7S/c1-11-9-26(10-22-11)17-4-2-3-16(23-17)14-8-21-15-6-5-12(7-13(14)15)18-24-25-19(20)27-18/h2-10,21H,1H3,(H2,20,25)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.42	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair