BDBM224980 US9321756, 247

SMILES: C1CC1c1cncc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(NC2CNC2)o1

InChI Key: InChIKey=UVJRFPDIIZDNQE-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 224980   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-3 (Homo sapiens (Human))	BDBM224980 (US9321756, 247) Show SMILES C1CC1c1cncc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(NC2CNC2)o1 Show InChI InChI=1S/C20H19N7O/c1-2-11(1)17-9-22-10-18(25-17)15-8-23-16-4-3-12(5-14(15)16)19-26-27-20(28-19)24-13-6-21-7-13/h3-5,8-11,13,21,23H,1-2,6-7H2,(H,24,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.346	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM224980 (US9321756, 247) Show SMILES C1CC1c1cncc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(NC2CNC2)o1 Show InChI InChI=1S/C20H19N7O/c1-2-11(1)17-9-22-10-18(25-17)15-8-23-16-4-3-12(5-14(15)16)19-26-27-20(28-19)24-13-6-21-7-13/h3-5,8-11,13,21,23H,1-2,6-7H2,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.05	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM224980 (US9321756, 247) Show SMILES C1CC1c1cncc(n1)-c1c[nH]c2ccc(cc12)-c1nnc(NC2CNC2)o1 Show InChI InChI=1S/C20H19N7O/c1-2-11(1)17-9-22-10-18(25-17)15-8-23-16-4-3-12(5-14(15)16)19-26-27-20(28-19)24-13-6-21-7-13/h3-5,8-11,13,21,23H,1-2,6-7H2,(H,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.34	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair