BDBM225014 US9321756, 281

SMILES: CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3ncc(C(N)=O)c(n3)C3CC3)c2c1

InChI Key: InChIKey=PJKHDASUTSMYOR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM225014 (US9321756, 281) Show SMILES CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3ncc(C(N)=O)c(n3)C3CC3)c2c1 Show InChI InChI=1S/C21H21N7O2/c1-10(2)25-21-28-27-20(30-21)12-5-6-16-13(7-12)14(8-23-16)19-24-9-15(18(22)29)17(26-19)11-3-4-11/h5-11,23H,3-4H2,1-2H3,(H2,22,29)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.15	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM225014 (US9321756, 281) Show SMILES CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3ncc(C(N)=O)c(n3)C3CC3)c2c1 Show InChI InChI=1S/C21H21N7O2/c1-10(2)25-21-28-27-20(30-21)12-5-6-16-13(7-12)14(8-23-16)19-24-9-15(18(22)29)17(26-19)11-3-4-11/h5-11,23H,3-4H2,1-2H3,(H2,22,29)(H,25,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair