BDBM225033 US9321756, 300

SMILES: CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3cc(=O)[nH]c(n3)C3CC3)c2c1

InChI Key: InChIKey=SEZAIJZBNCLTIN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM225033 (US9321756, 300) Show SMILES CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3cc(=O)[nH]c(n3)C3CC3)c2c1 Show InChI InChI=1S/C20H20N6O2/c1-10(2)22-20-26-25-19(28-20)12-5-6-15-13(7-12)14(9-21-15)16-8-17(27)24-18(23-16)11-3-4-11/h5-11,21H,3-4H2,1-2H3,(H,22,26)(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.24	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM225033 (US9321756, 300) Show SMILES CC(C)Nc1nnc(o1)-c1ccc2[nH]cc(-c3cc(=O)[nH]c(n3)C3CC3)c2c1 Show InChI InChI=1S/C20H20N6O2/c1-10(2)22-20-26-25-19(28-20)12-5-6-15-13(7-12)14(9-21-15)16-8-17(27)24-18(23-16)11-3-4-11/h5-11,21H,3-4H2,1-2H3,(H,22,26)(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
AMGEN INC. US Patent					Assay Description The assay for the determination of Pim activity is based on the formation of phosphorylated biotinylated-BAD peptide at the Serine 112 residue (S112)...				US Patent US9321756 (2016) BindingDB Entry DOI: 10.7270/Q2W094S2
					More data for this Ligand-Target Pair