BDBM225273 2-[4-(4-Methylpiperazin-1-yl)phenyl]-1H-benzo[d]imidazole (3a)

SMILES: CN1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1

InChI Key: InChIKey=MTCZGPPSHVGCKQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Homo sapiens (Human))	BDBM225273 (2-[4-(4-Methylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)15-8-6-14(7-9-15)18-19-16-4-2-3-5-17(16)20-18/h2-9H,10-13H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	8.0	25
Hacettepe University					Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...				Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK
					More data for this Ligand-Target Pair
Butyrylcholinesterase (BChE) (Equus caballus (Horse))	BDBM225273 (2-[4-(4-Methylpiperazin-1-yl)phenyl]-1H-benzo[d]im...) Show SMILES CN1CCN(CC1)c1ccc(cc1)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C18H20N4/c1-21-10-12-22(13-11-21)15-8-6-14(7-9-15)18-19-16-4-2-3-5-17(16)20-18/h2-9H,10-13H2,1H3,(H,19,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	8.0	25
Hacettepe University					Assay Description Reactions were performed in a mediumcontaining substrate (0.05-0.4 mM) combined with 0.125 mM DTNB in 100 mM 3-(N-morpholino)propanesulfonic acid buf...				Bioorg Chem 72: 208-214 (2017) BindingDB Entry DOI: 10.7270/Q2JM28HK
					More data for this Ligand-Target Pair