BDBM225286 1,1''-bis(3-Fluorobenzyl)-1H,1''H-[3,3':3',3''-terindol]-2'(1'H)-one (4g)
SMILES: Fc1cccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3cccc(F)c3)c3ccccc23)c1
InChI Key: InChIKey=NOTJQPWERSCRBF-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM225286 (1,1''-bis(3-Fluorobenzyl)-1H,1''H-...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr... | Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
alpha-Glucosidase (alpha-Glu) (Saccharomyces cerevisiae) | BDBM225286 (1,1''-bis(3-Fluorobenzyl)-1H,1''H-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | n/a | n/a | 7.92E+3 | n/a | n/a | n/a | n/a | 6.8 | 37 | |
Jishou University | Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco... | Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV | |||||||||||
More data for this Ligand-Target Pair |