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SMILES: Brc1ccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3ccc(Br)cc3)c3ccccc23)cc1

InChI Key: InChIKey=AYZGRJQDYRJYCS-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225287   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM225287 (1,1''-bis(4-Bromobenzyl)-1H,1''H-[...) Show SMILES Brc1ccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3ccc(Br)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C38H27Br2N3O/c39-27-17-13-25(14-18-27)21-42-23-32(29-7-1-5-11-35(29)42)38(31-9-3-4-10-34(31)41-37(38)44)33-24-43(36-12-6-2-8-30(33)36)22-26-15-19-28(40)20-16-26/h1-20,23-24H,21-22H2,(H,41,44)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using p-nitrophenyl-alpha-d-glucopyranoside as substrate preincubated for 15 mins followed by substr...				Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Saccharomyces cerevisiae)	BDBM225287 (1,1''-bis(4-Bromobenzyl)-1H,1''H-[...) Show SMILES Brc1ccc(Cn2cc(c3ccccc23)C2(C(=O)Nc3ccccc23)c2cn(Cc3ccc(Br)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C38H27Br2N3O/c39-27-17-13-25(14-18-27)21-42-23-32(29-7-1-5-11-35(29)42)38(31-9-3-4-10-34(31)41-37(38)44)33-24-43(36-12-6-2-8-30(33)36)22-26-15-19-28(40)20-16-26/h1-20,23-24H,21-22H2,(H,41,44)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	9.16E+3	n/a	n/a	n/a	n/a	6.8	37
Jishou University					Assay Description The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...				Bioorg Chem 72: 228-233 (2017) BindingDB Entry DOI: 10.7270/Q2DV1HSV
					More data for this Ligand-Target Pair