BDBM22529 2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-4,5-dihydro-1,3-oxazole::4-Benzyl-1H-imidazole derivative, 10

SMILES: CC1(C)COC(=N1)c1cccc(Cc2cnc[nH]2)c1

InChI Key: InChIKey=ZNVMEAWYMJXRHW-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM22529 (2-[3-(1H-imidazol-4-ylmethyl)phenyl]-4,4-dimethyl-...) Show SMILES CC1(C)COC(=N1)c1cccc(Cc2cnc[nH]2)c1 |c:5| Show InChI InChI=1S/C15H17N3O/c1-15(2)9-19-14(18-15)12-5-3-4-11(6-12)7-13-8-16-10-17-13/h3-6,8,10H,7,9H2,1-2H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4	-11.4	n/a	n/a	16	n/a	n/a	7.4	25
VU University Amsterdam					Assay Description Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...				J Med Chem 51: 2944-53 (2008) Article DOI: 10.1021/jm7014149 BindingDB Entry DOI: 10.7270/Q24F1P2W
					More data for this Ligand-Target Pair