BDBM225333 Chk1_4

SMILES: COc1cc2Cc3c(n[nH]c3-c3ccc(O)cc3)-c2cc1OC

InChI Key: InChIKey=YXCSLEHSWRLDHG-UHFFFAOYSA-N

Data: 2 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 [2-280] (Homo sapiens (Human))	BDBM225333 (Chk1_4) Show SMILES COc1cc2Cc3c(n[nH]c3-c3ccc(O)cc3)-c2cc1OC Show InChI InChI=1S/C18H16N2O3/c1-22-15-8-11-7-14-17(10-3-5-12(21)6-4-10)19-20-18(14)13(11)9-16(15)23-2/h3-6,8-9,21H,7H2,1-2H3,(H,19,20)	PDB GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB D3R	23.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description 33P-Radiometric_Method1				D3R 221: (2015) BindingDB Entry DOI: 10.7270/Q2WS8S4Z
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase Chk1 [2-280] (Homo sapiens (Human))	BDBM225333 (Chk1_4) Show SMILES COc1cc2Cc3c(n[nH]c3-c3ccc(O)cc3)-c2cc1OC Show InChI InChI=1S/C18H16N2O3/c1-22-15-8-11-7-14-17(10-3-5-12(21)6-4-10)19-20-18(14)13(11)9-16(15)23-2/h3-6,8-9,21H,7H2,1-2H3,(H,19,20)	PDB GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB D3R	178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description 33P-Radiometric_Method1				D3R 221: (2015) BindingDB Entry DOI: 10.7270/Q2WS8S4Z
					More data for this Ligand-Target Pair				3D Structure (crystal)