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BDBM22534 2-[3-(1H-imidazol-4-ylmethyl)phenyl]pyridine::4-Benzyl-1H-imidazole derivative, 15

SMILES: C(c1cnc[nH]1)c1cccc(c1)-c1ccccn1

InChI Key: InChIKey=KNNVBHWBIFXMDF-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22534   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM22534
PNG
(2-[3-(1H-imidazol-4-ylmethyl)phenyl]pyridine | 4-B...)
Show SMILES C(c1cnc[nH]1)c1cccc(c1)-c1ccccn1
Show InChI InChI=1S/C15H13N3/c1-2-7-17-15(6-1)13-5-3-4-12(8-13)9-14-10-16-11-18-14/h1-8,10-11H,9H2,(H,16,18)
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KEGG

UniProtKB/SwissProt

DrugBank
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GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
41 -10.1n/an/an/an/an/a7.425



VU University Amsterdam



Assay Description
Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...


J Med Chem 51: 2944-53 (2008)


Article DOI: 10.1021/jm7014149
BindingDB Entry DOI: 10.7270/Q24F1P2W
More data for this
Ligand-Target Pair