BDBM225374 Chk1_135

SMILES: CCc1ccc(CCOc2cc3Cc4c(n[nH]c4-c4ccc(cc4)-c4ccc(O)cc4)-c3cc2OC)nc1

InChI Key: InChIKey=JEVGZWNOZXXJPR-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 225374   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CHK1_Kinase (Homo sapiens (Human))	BDBM225374 (Chk1_135) Show SMILES CCc1ccc(CCOc2cc3Cc4c(n[nH]c4-c4ccc(cc4)-c4ccc(O)cc4)-c3cc2OC)nc1 Show InChI InChI=1S/C32H29N3O3/c1-3-20-4-11-25(33-19-20)14-15-38-30-17-24-16-28-31(34-35-32(28)27(24)18-29(30)37-2)23-7-5-21(6-8-23)22-9-12-26(36)13-10-22/h4-13,17-19,36H,3,14-16H2,1-2H3,(H,34,35)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	23.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description 33P-Radiometric_Method1				D3R 221: (2015) BindingDB Entry DOI: 10.7270/Q2WS8S4Z
					More data for this Ligand-Target Pair