BDBM22540 4-Benzyl-1H-imidazole derivative, 21::4-{[3-(pent-1-yn-1-yl)phenyl]methyl}-1H-imidazole

SMILES: CCCC#Cc1cccc(Cc2cnc[nH]2)c1

InChI Key: InChIKey=JAPGJDHRYBFKBD-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22540   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM22540 (4-Benzyl-1H-imidazole derivative, 21 | 4-{[3-(pent...) Show SMILES CCCC#Cc1cccc(Cc2cnc[nH]2)c1 Show InChI InChI=1S/C15H16N2/c1-2-3-4-6-13-7-5-8-14(9-13)10-15-11-16-12-17-15/h5,7-9,11-12H,2-3,10H2,1H3,(H,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3	-11.6	n/a	n/a	n/a	n/a	n/a	7.4	25
VU University Amsterdam					Assay Description Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...				J Med Chem 51: 2944-53 (2008) Article DOI: 10.1021/jm7014149 BindingDB Entry DOI: 10.7270/Q24F1P2W
					More data for this Ligand-Target Pair