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BDBM22540 4-Benzyl-1H-imidazole derivative, 21::4-{[3-(pent-1-yn-1-yl)phenyl]methyl}-1H-imidazole

SMILES: CCCC#Cc1cccc(Cc2cnc[nH]2)c1

InChI Key: InChIKey=JAPGJDHRYBFKBD-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22540   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM22540
PNG
(4-Benzyl-1H-imidazole derivative, 21 | 4-{[3-(pent...)
Show SMILES CCCC#Cc1cccc(Cc2cnc[nH]2)c1
Show InChI InChI=1S/C15H16N2/c1-2-3-4-6-13-7-5-8-14(9-13)10-15-11-16-12-17-15/h5,7-9,11-12H,2-3,10H2,1H3,(H,16,17)
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
3 -11.6n/an/an/an/an/a7.425



VU University Amsterdam



Assay Description
Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...


J Med Chem 51: 2944-53 (2008)


Article DOI: 10.1021/jm7014149
BindingDB Entry DOI: 10.7270/Q24F1P2W
More data for this
Ligand-Target Pair