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BDBM22547 4-(1H-imidazol-4-ylmethyl)aniline::4-Benzyl-1H-imidazole derivative, 25

SMILES: Nc1ccc(Cc2cnc[nH]2)cc1

InChI Key: InChIKey=LKKISAMEUBGGRO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22547   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine receptor (H3)


(Homo sapiens (Human))
BDBM22547
PNG
(4-(1H-imidazol-4-ylmethyl)aniline | 4-Benzyl-1H-im...)
Show SMILES Nc1ccc(Cc2cnc[nH]2)cc1
Show InChI InChI=1S/C10H11N3/c11-9-3-1-8(2-4-9)5-10-6-12-7-13-10/h1-4,6-7H,5,11H2,(H,12,13)
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Patents

Article
PubMed
257 -8.98n/an/an/an/an/a7.425



VU University Amsterdam



Assay Description
Ligand displacement assays were performed on CHO cells membranes expressing hH3R. Retained radioactivity was determined by liquid scintillation count...


J Med Chem 51: 2944-53 (2008)


Article DOI: 10.1021/jm7014149
BindingDB Entry DOI: 10.7270/Q24F1P2W
More data for this
Ligand-Target Pair