null

SMILES: Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12

InChI Key: InChIKey=HYISMXPRENTEMF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225528   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225528 (GTC000234A) Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12 Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	4.79	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225528 (GTC000234A) Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12 Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	1.87	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225528 (GTC000234A) Show SMILES Cc1nn(CCCO)c2cc(Nc3ncc(F)c(n3)N(CCCO)c3cccc4[nH]ncc34)ccc12 Show InChI InChI=1S/C25H27FN8O2/c1-16-18-8-7-17(13-23(18)34(32-16)10-4-12-36)29-25-27-15-20(26)24(30-25)33(9-3-11-35)22-6-2-5-21-19(22)14-28-31-21/h2,5-8,13-15,35-36H,3-4,9-12H2,1H3,(H,28,31)(H,27,29,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	2.46	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair