null

SMILES: OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F

InChI Key: InChIKey=AAMIJOPUOOWLFX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 225529   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225529 (GTC000235A) Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	9.64	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225529 (GTC000235A) Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	1.64	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225529 (GTC000235A) Show SMILES OCCCCN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CCS(=O)(=O)c3c2)ncc1F Show InChI InChI=1S/C23H23FN6O3S/c24-18-14-25-23(27-16-7-6-15-8-11-34(32,33)21(15)12-16)28-22(18)30(9-1-2-10-31)20-5-3-4-19-17(20)13-26-29-19/h3-7,12-14,31H,1-2,8-11H2,(H,26,29)(H,25,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	D3R	n/a	n/a	1.94	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair