null

SMILES: CN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F

InChI Key: InChIKey=AKKNJEBKJABIRC-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225545   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225545 (GTC000249A) Show SMILES CN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F Show InChI InChI=1S/C19H16FN7O2S/c1-27(16-4-2-3-15-13(16)9-22-26-15)18-14(20)10-21-19(25-18)24-12-6-5-11-8-23-30(28,29)17(11)7-12/h2-7,9-10,23H,8H2,1H3,(H,22,26)(H,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB D3R	n/a	n/a	1.99	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein kinase SYK [355-635] (Homo sapiens (Human))	BDBM225545 (GTC000249A) Show SMILES CN(c1cccc2[nH]ncc12)c1nc(Nc2ccc3CNS(=O)(=O)c3c2)ncc1F Show InChI InChI=1S/C19H16FN7O2S/c1-27(16-4-2-3-15-13(16)9-22-26-15)18-14(20)10-21-19(25-18)24-12-6-5-11-8-23-30(28,29)17(11)7-12/h2-7,9-10,23H,8H2,1H3,(H,22,26)(H,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB D3R	n/a	n/a	11.6	n/a	n/a	n/a	n/a	n/a	n/a
D3R					Assay Description SYK assay_HTRF				D3R 225: (2015) BindingDB Entry DOI: 10.7270/Q2CV4GM1
					More data for this Ligand-Target Pair				3D Structure (crystal)