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BDBM22642 2-[4-(ethylcarbamoyl)-1-methylpiperazin-2-yl]-N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-Me-pyrimidone deriv., 41

SMILES: CCNC(=O)N1CCN(C)C(C1)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C

InChI Key: InChIKey=GKNZGRCDXKQFMJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22642   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein


(Human immunodeficiency virus type 1 group M subtyp...)		BDBM22642
PNG
(2-[4-(ethylcarbamoyl)-1-methylpiperazin-2-yl]-N-[(...)
Show SMILES CCNC(=O)N1CCN(C)C(C1)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C
Show InChI InChI=1S/C21H27FN6O4/c1-4-23-21(32)28-10-9-26(2)15(12-28)18-25-16(17(29)20(31)27(18)3)19(30)24-11-13-5-7-14(22)8-6-13/h5-8,15,29H,4,9-12H2,1-3H3,(H,23,32)(H,24,30)
PDB
MMDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 52n/an/an/an/an/an/a



IRBM-MRL



Assay Description
The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...

J Med Chem 50: 4953-75 (2007)


Article DOI: 10.1021/jm0704705
BindingDB Entry DOI: 10.7270/Q2BZ64BS
More data for this
Ligand-Target Pair