BDBM22650 N-Me-pyrimidone deriv., 49::tert-butyl 3-(4-{[(4-fluorophenyl)methyl]carbamoyl}-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl)morpholine-4-carboxylate

SMILES: Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C1COCCN1C(=O)OC(C)(C)C

InChI Key: InChIKey=ZUUXMVZRRTYKLW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22650   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22650 (N-Me-pyrimidone deriv., 49 | tert-butyl 3-(4-{[(4-...) Show SMILES Cn1c(nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O)C1COCCN1C(=O)OC(C)(C)C Show InChI InChI=1S/C22H27FN4O6/c1-22(2,3)33-21(31)27-9-10-32-12-15(27)18-25-16(17(28)20(30)26(18)4)19(29)24-11-13-5-7-14(23)8-6-13/h5-8,15,28H,9-12H2,1-4H3,(H,24,29)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 50: 4953-75 (2007) Article DOI: 10.1021/jm0704705 BindingDB Entry DOI: 10.7270/Q2BZ64BS
					More data for this Ligand-Target Pair