BDBM22661 N-Me-pyrimidone deriv., 60::N-[(3-chloro-4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-(4-methylmorpholin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide

SMILES: CN1CCOCC1c1nc(C(=O)NCc2ccc(F)c(Cl)c2)c(O)c(=O)n1C

InChI Key: InChIKey=XUQLPYKTRJNHSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22661   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22661 (N-Me-pyrimidone deriv., 60 | N-[(3-chloro-4-fluoro...) Show SMILES CN1CCOCC1c1nc(C(=O)NCc2ccc(F)c(Cl)c2)c(O)c(=O)n1C Show InChI InChI=1S/C18H20ClFN4O4/c1-23-5-6-28-9-13(23)16-22-14(15(25)18(27)24(16)2)17(26)21-8-10-3-4-12(20)11(19)7-10/h3-4,7,13,25H,5-6,8-9H2,1-2H3,(H,21,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 50: 4953-75 (2007) Article DOI: 10.1021/jm0704705 BindingDB Entry DOI: 10.7270/Q2BZ64BS
					More data for this Ligand-Target Pair