BDBM22666 8-(dimethylamino)-N-[(4-fluorophenyl)methyl]-3-hydroxy-4-oxo-4H,6H,7H,8H-pyrrolo[1,2-a]pyrimidine-2-carboxamide::Bicyclic pyrimidinone, 7a

SMILES: CN(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O

InChI Key: InChIKey=DCFNUDUWQUUVTO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22666 (8-(dimethylamino)-N-[(4-fluorophenyl)methyl]-3-hyd...) Show SMILES CN(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O Show InChI InChI=1S/C17H19FN4O3/c1-21(2)12-7-8-22-15(12)20-13(14(23)17(22)25)16(24)19-9-10-3-5-11(18)6-4-10/h3-6,12,23H,7-9H2,1-2H3,(H,19,24)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	7.8	37
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 51: 861-74 (2008) Article DOI: 10.1021/jm701164t BindingDB Entry DOI: 10.7270/Q2765CNT
					More data for this Ligand-Target Pair