BDBM22692 Bicyclic pyrimidinone, 21b::N-[(4-fluorophenyl)methyl]-3-hydroxy-9-[methyl(1,3,5-trimethyl-1H-pyrazole-4-)sulfonamido]-4-oxo-4H,6H,7H,8H,9H-pyrido[1,2-a]pyrimidine-2-carboxamide

SMILES: CN(C1CCCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O)S(=O)(=O)c1c(C)nn(C)c1C

InChI Key: InChIKey=UMFNMQJGSPMGBC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 22692   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein (Human immunodeficiency virus type 1 group M subtyp...)	BDBM22692 (Bicyclic pyrimidinone, 21b | N-[(4-fluorophenyl)me...) Show SMILES CN(C1CCCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O)S(=O)(=O)c1c(C)nn(C)c1C Show InChI InChI=1S/C23H27FN6O5S/c1-13-20(14(2)28(3)27-13)36(34,35)29(4)17-6-5-11-30-21(17)26-18(19(31)23(30)33)22(32)25-12-15-7-9-16(24)10-8-15/h7-10,17,31H,5-6,11-12H2,1-4H3,(H,25,32)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
IRBM-MRL					Assay Description The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...				J Med Chem 51: 861-74 (2008) Article DOI: 10.1021/jm701164t BindingDB Entry DOI: 10.7270/Q2765CNT
					More data for this Ligand-Target Pair