BDBM2272 2-Pyridinone derivative 52::3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-(hydroxymethyl)-6-methyl-1,2-dihydropyridin-2-one::3-[2-(Benzoxazold-yl)ethy1]-5-(hydroxymethyl)-6-methylpyridin-2(1H)-one::CHEMBL367204

SMILES: Cc1[nH]c(=O)c(CCc2nc3ccccc3o2)cc1CO

InChI Key: InChIKey=YXTBBWMFLQLECP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2272   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM2272 (2-Pyridinone derivative 52 | 3-[2-(1,3-benzoxazol-...) Show SMILES Cc1[nH]c(=O)c(CCc2nc3ccccc3o2)cc1CO Show InChI InChI=1S/C16H16N2O3/c1-10-12(9-19)8-11(16(20)17-10)6-7-15-18-13-4-2-3-5-14(13)21-15/h2-5,8,19H,6-7,9H2,1H3,(H,17,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description Tested for inhibition against HIV-1 RT (used (poly)rC-(oligo)dG as the template)				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM2272 (2-Pyridinone derivative 52 | 3-[2-(1,3-benzoxazol-...) Show SMILES Cc1[nH]c(=O)c(CCc2nc3ccccc3o2)cc1CO Show InChI InChI=1S/C16H16N2O3/c1-10-12(9-19)8-11(16(20)17-10)6-7-15-18-13-4-2-3-5-14(13)21-15/h2-5,8,19H,6-7,9H2,1H3,(H,17,20)	PDB MMDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Reserch Laboratories Curated by ChEMBL					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 36: 953-66 (1993) BindingDB Entry DOI: 10.7270/Q2JW8G28
					More data for this Ligand-Target Pair