BDBM227516 US9334278, I-5

SMILES: Cn1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1

InChI Key: InChIKey=WQVAPHCMGOOMKB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 227516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
SYK RPA purified, truncated construct of Spleen Tyrosine Kinase (aa 360-635) (Homo sapiens (Human))	BDBM227516 (US9334278, I-5) Show SMILES Cn1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1 Show InChI InChI=1S/C15H19N7O/c1-15(2,3)21-14(23)10-6-16-13-12(10)20-11(7-17-13)19-9-5-18-22(4)8-9/h5-8H,1-4H3,(H,16,17)(H,19,20)(H,21,23)	PDB GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13.7	n/a	n/a	n/a	n/a	n/a	30
Hoffmann-La Roche Inc. US Patent					Assay Description Assay plates: 96-well MultiScreen 0.65 μm filter plates (Millipore Cat. No.: MADVNOB 10) Streptavidin coated beads: Streptavidin Sepharose™,...				US Patent US9334278 (2016) BindingDB Entry DOI: 10.7270/Q2JD4VN3
					More data for this Ligand-Target Pair