BDBM227584 2-Fluoro-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]benzamide hydrochloride (3c)
SMILES: Fc1ccccc1C(=O)NCCCCNc1c2CCCCc2nc2ccccc12
InChI Key: InChIKey=GKFHMEQQMKLVMW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Butyrylcholinesterase (BChE) (Equus caballus (Horse)) | BDBM227584 (2-Fluoro-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.39 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Medical University of Lodz | Assay Description The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c... | Bioorg Chem 72: 315-322 (2017) Article DOI: 10.1016/j.bioorg.2017.05.003 BindingDB Entry DOI: 10.7270/Q2RX99ZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM227584 (2-Fluoro-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 41.4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Medical University of Lodz | Assay Description The test was run as described in the following procedure: stock solution of the test compounds was diluted in phosphate buffer pH 7.4 to give final c... | Bioorg Chem 72: 315-322 (2017) Article DOI: 10.1016/j.bioorg.2017.05.003 BindingDB Entry DOI: 10.7270/Q2RX99ZF | |||||||||||
More data for this Ligand-Target Pair |