null

SMILES: CCN(CCO)Cc1ccc2Nc3nccc(Nc4cc(O)c(Cl)cc4F)c3C(=O)Nc2c1

InChI Key: InChIKey=JRHZSLDMBCJCRQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 227829   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM227829 (4-[(4-Chloro-2-fluoro-5-hydroxyphenyl)amino]-8-{[e...) Show SMILES CCN(CCO)Cc1ccc2Nc3nccc(Nc4cc(O)c(Cl)cc4F)c3C(=O)Nc2c1 Show InChI InChI=1S/C23H23ClFN5O3/c1-2-30(7-8-31)12-13-3-4-16-19(9-13)29-23(33)21-17(5-6-26-22(21)28-16)27-18-11-20(32)14(24)10-15(18)25/h3-6,9-11,31-32H,2,7-8,12H2,1H3,(H,29,33)(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.793	n/a	n/a	n/a	n/a	7.5	22
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human PDGFRβ (amino acids R561-L1106), expr...				US Patent US10047096 (2018) BindingDB Entry DOI: 10.7270/Q23R0VW4
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM227829 (4-[(4-Chloro-2-fluoro-5-hydroxyphenyl)amino]-8-{[e...) Show SMILES CCN(CCO)Cc1ccc2Nc3nccc(Nc4cc(O)c(Cl)cc4F)c3C(=O)Nc2c1 Show InChI InChI=1S/C23H23ClFN5O3/c1-2-30(7-8-31)12-13-3-4-16-19(9-13)29-23(33)21-17(5-6-26-22(21)28-16)27-18-11-20(32)14(24)10-15(18)25/h3-6,9-11,31-32H,2,7-8,12H2,1H3,(H,29,33)(H2,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.31	n/a	n/a	n/a	n/a	7.0	n/a
Bayer Pharma Aktiengesellschaft US Patent					Assay Description The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...				US Patent US10047096 (2018) BindingDB Entry DOI: 10.7270/Q23R0VW4
					More data for this Ligand-Target Pair