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SMILES: Clc1ccc2[nH]c(CS(=O)c3ccccc3)c(Sc3ccccc3)c2c1

InChI Key: InChIKey=JSXXSKIISLBDCU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2280   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gag-Pol polyprotein [588-1027]/[588-1147]


(Human immunodeficiency virus type 1)		BDBM2280
PNG
(2-[(benzenesulfinyl)methyl]-5-chloro-3-(phenylsulf...)
Show SMILES Clc1ccc2[nH]c(CS(=O)c3ccccc3)c(Sc3ccccc3)c2c1
Show InChI InChI=1S/C21H16ClNOS2/c22-15-11-12-19-18(13-15)21(25-16-7-3-1-4-8-16)20(23-19)14-26(24)17-9-5-2-6-10-17/h1-13,23H,14H2
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PC cid
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UniChem

Similars
Article
PubMed
n/an/a 112n/an/an/an/a8.2n/a



Merck Research Laboratories



Assay Description
The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.

J Med Chem 36: 1291-4 (1993)


Article DOI: 10.1021/jm00061a022
BindingDB Entry DOI: 10.7270/Q2RV0KWR
More data for this
Ligand-Target Pair