null

SMILES: Cn1cc(OC2CN(C2)c2cccc(COC(=O)CC(N)=N)c2F)ccc1=O

InChI Key: InChIKey=CBFHNKKBGWOWIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM228096 (US9556160, ex 557) Show SMILES Cn1cc(OC2CN(C2)c2cccc(COC(=O)CC(N)=N)c2F)ccc1=O Show InChI InChI=1S/C19H21FN4O4/c1-23-8-13(5-6-17(23)25)28-14-9-24(10-14)15-4-2-3-12(19(15)20)11-27-18(26)7-16(21)22/h2-6,8,14H,7,9-11H2,1H3,(H3,21,22)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A rat VAP-1 enzyme (SSAO) (reference: Biol Pharm Bull. 2005 March; 28(3): 413-8) activity was measured by a radiochemistry-enzymatic assay using 14C-...				US Patent US9556160 (2017) BindingDB Entry DOI: 10.7270/Q2KP845Q
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Homo sapiens (Human))	BDBM228096 (US9556160, ex 557) Show SMILES Cn1cc(OC2CN(C2)c2cccc(COC(=O)CC(N)=N)c2F)ccc1=O Show InChI InChI=1S/C19H21FN4O4/c1-23-8-13(5-6-17(23)25)28-14-9-24(10-14)15-4-2-3-12(19(15)20)11-27-18(26)7-16(21)22/h2-6,8,14H,7,9-11H2,1H3,(H3,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	25
Astellas Pharma Inc. US Patent					Assay Description A human VAP-1 enzyme (SSAO) (reference: J Exp Med. 1998 Jul. 6; 188(1): 17 to 27) activity was measured by a radiochemistry-enzymatic assay using 14C...				US Patent US9556160 (2017) BindingDB Entry DOI: 10.7270/Q2KP845Q
					More data for this Ligand-Target Pair