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SMILES: FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1(CN2CCC3(CC3)CC2)CC1

InChI Key: InChIKey=BIULWZLYCZLVJY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228163   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 4


(Homo sapiens (Human))		BDBM228163
PNG
(US10047073, 5)
Show SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1(CN2CCC3(CC3)CC2)CC1
Show InChI InChI=1S/C21H23F3N4O2/c22-21(23,24)18-25-16(27-30-18)14-1-3-15(4-2-14)17(29)26-20(7-8-20)13-28-11-9-19(5-6-19)10-12-28/h1-4H,5-13H2,(H,26,29)
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MMDB

KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 89n/an/an/an/an/an/a



CHDI FOUNDATION, INC

US Patent


Assay Description
The Class I HDAC activity of Class IIa Histone Deacetylase (HDAC) inhibitors was quantified by measuring the cellular histone deacetylase enzymatic a...

US Patent US10047073 (2018)


BindingDB Entry DOI: 10.7270/Q2PG1TQC
More data for this
Ligand-Target Pair