BDBM228169 US10047073, 9

SMILES: FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1(CN2CCC3(CC3)C2)CCC1

InChI Key: InChIKey=KDTCSZKKTPRSAS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 228169   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM228169 (US10047073, 9) Show SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1(CN2CCC3(CC3)C2)CCC1 Show InChI InChI=1S/C21H23F3N4O2/c22-21(23,24)18-25-16(27-30-18)14-2-4-15(5-3-14)17(29)26-20(6-1-7-20)13-28-11-10-19(12-28)8-9-19/h2-5H,1,6-13H2,(H,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
CHDI FOUNDATION, INC US Patent					Assay Description The Class I HDAC activity of Class IIa Histone Deacetylase (HDAC) inhibitors was quantified by measuring the cellular histone deacetylase enzymatic a...				US Patent US10047073 (2018) BindingDB Entry DOI: 10.7270/Q2PG1TQC
					More data for this Ligand-Target Pair